单冒号(:)用于CSS3伪类，双冒号(::)用于CSS3伪元素。

W3C关于CSS3选择器的规范中有一段描述：

A pseudo-element is made of two colons (::) followed by the name of the pseudo-element.
This :: notation is introduced by the current document in order to establish a discrimination between pseudo-classes and pseudo-elements. For compatibility with existing style sheets, user agents must also accept the previous one-colon notation for pseudo-elements introduced in CSS levels 1 and 2 (namely, :first-line, :first-letter, :before and :after). This compatibility is not allowed for the new pseudo-elements introduced in CSS level 3.

大意就是：伪元素由双冒号和伪元素名称组成。双冒号是在当前规范中引入的，用于区分伪类和伪元素。不过浏览器需要同时支持旧的已经存在的伪元素写法，比如:first-line、:first-letter、:before、:after等，而新的在CSS3中引入的伪元素则不允许再支持旧的单冒号的写法。

对于CSS2之前已有的伪元素，比如:before，单冒号和双冒号的写法::before作用是一样的。

所以，如果你的网站只需要兼容webkit、firefox、opera等浏览器，建议对于伪元素采用双冒号的写法，如果不得不兼容IE浏览器，还是用CSS2的单冒号写法比较安全。